Objective: to obtain pilot data on efficacy and safety of multiple different Perampanel dual therapy anticonvulsant combinatorial treatment of adults with refractory focal epilepsy.

Inclusion criteria

  • Age 18-65
  • Focal epilepsy
  • Past/current treatment with 4 AEDs. VNS allowed.
  • Seizure frequency of ≥1/month


Mid-Atlantic Epilepsy & Sleep Center
Pavel Klein, M.D.

Ivana Tyrlikova, Arkady Barber, Lenka Goldman, study coordinators
Phone: 301 530 9744
Fax: 301 530 0046